بررسی عوامل خطر در پسودواکسفولیشن چشم

Bِackground and Aim: Pseudoexfoliation syndrome is the most common identifiable cause of open angle glaucoma's worldwide. Despite its prevalence and potential for ophthalmic morbidity, little is known about the etiology and the pathogenesis of pseudoexfoliation. The aim of this study was to investigate the risk factor of pseudoexfoliation in all admitted patients to eye clinic. Materials and Methods: In this descriptive study, during 6 months, a questionnaire check list was completed for 100 referrals to eye clinic that their ophthalmic examination revealed pseudoexfoliation residues in their eyes. The checklist consists of possible risk factors including demographic, ultraviolet-rays, trauma, cardiovascular disease, hypertension, and diabetes. The collected data was analyzed by descriptive statistical methods like chi-Square tests using SPSS version 9.0 with P=0.05 as the minimum statistical significance. Results: Forty six percent of patients were male and the rest were females. History of hypertension was present in 19 cases, 4 cases had cardiovascular disease and one had diabetes mellitus. A majority of them (66.07%) of them were from rural area and 27.9% were from urban who had a history of sunlight contact less than 2 hours per day. Of 46 farmer patients 72.09% had sunlight contact more than 4 hours per day. Conclusion: This study showed that pseudoexfoliation is more prevalent in females, and that the farmers had more exposure to ultraviolet radiation. Contact of farmers with animal viruses, poisons, chemical agents and hard physical work should be regarded as predisposing factors. Because of the limitation of this study, descriptive and case-control studies with more population must be undertaken in the future